Current Projects
Gene Therapy
- Targeted Therapy for Small Cell Lung Cancer
- Identification of tumor suppressor gene candidates in SCLC, which alone or combined with p53 reactivating molecules can be used in cancer gene therapy
Growth Factors
- Role of Different Signalling Pathways Downstream of a Truncated Epidermal Growth Factor Receptor
- The Role of EphA2 in EGFR/EGFRvIII Mediated Tumor Transformation
Gliomas
- Establishment in vitro and in vivo models of glioblastomas
- Effects of EGFR and VEGF inhibition in human glioblastoma cells using cetuximab in combination with bevacizumab
- Cross-talk between EGFR signaling and the Notch pathway in glioblastoma multiforme
- The role of Notch signaling in brain cancer stem-like cells and glioblastoma multiforme
- Production of the bivalent D2C7 immunotoxin for treatment of Glioblastoma Multiforme