Latest Publications

2010:
Kosteljanetz M, Poulsen HS. Ugeskrift for Læger. 2010 Jan 18;172(3):214-217.
(click here to open pubmed link)

Marie-Thérése Stockhausen, Karina Kristoffersen, Hans S. Poulsen: “The
functional role of Notch Signaling in human gliomas”. Journal of
Neuro-Oncology, 2010;12(2):199-211
(Click here to open pubmed link)

Larsen AB, Stockhausen MT, Skovgaard H. Cell adhesion and EGFR activation
regulate EphA2 expression in cancer. Cellular Signalling, 2010;22, 636-644.
(click here to open pubmed link).

2009:
Poulsen HS, Grunnet K, Sorensen M, Olsen P, Hasselbalch B, Nelausen K,
Kosteljanetz M, Lassen U. Bevacizumab plus irinotecan in the treatment
patients with progressive recurrent malignant brain tumours. Acta Oncol,
2009; 48: 52-58. (click here to open pubmed link).

Camilla L. Christensen, Roza zandi, Torben Gjetting, Frederik Cramer, Hans S. Poulsen: Specifically targeted gene therapy for Small Cell Lung Cancer. Expert Review for Anticancer Therapy. Expert Rev. Anticancer Ther., 9 (4), 437-452 (2009). (click here to open pubmed link)

Denholt CL, Hansen PR, Pedersen N, Poulsen HS, Gillings N, Kjaer A.
Identification of novel peptide ligands for the cancer-specific receptor mutation EFGRvIII using a mixture-based synthetic combinatorial library. Biopolymers. 2009 Mar;91(3):201-6 (click here to open pubmed link)

Andersen P, Villingshøj M, Poulsen HS, Stockhausen MT.Improved Response by
Co-targeting EGFR/EGFRvIII and Src Family Kinases in Human Cancer Cells.
Cancer Invest. 2009 Feb;27(2):178-83 (click here to open pubmed link)

2008:
Hansen CL, Hansen PR, Pedersen N, Poulsen HS, Gillings N, Kjaer A. Identification of amino acid residues in PEPHC1 important for binding to the tumor-specific receptor EGFRvIII. Chem Biol Drug Des . 2008 Oct; 72 ( 4 ): 273-8 (click here to open pubmed link)

Poulsen TT, Naizhen X, Poulsen HS, Linnoila RI. Acute damage by naphthalene triggers expression of the neuroendocrine marker PGP9.5 in airway epithelial cells. Toxicology Letters , 181 (2): 67-74, 2008 (click here to open pubmed link)

Poulsen TT, Pappot H, Poulsen HS. Molecular Biology in Lung Cancer. Chapter 3 in IASLC Textbook on Lung Cancer 2nd edition, edited by Hansen HH, Informa Healthcare, London, UK

Poulsen TT, Pedersen N, Juel H, Poulsen HS. A chimeric fusion of the hASH1 and EZH2 promoters mediates high and specific reporter and suicide gene expression and cytotoxicity in small cell lung cancer cells . Cancer Gene Therapy, 15 (9):563-75. (click here to open pubmed link)

Andersen P, Pedersen MW, Woetmann A, Villingshøj, M, Stockhausen M, Ødum N and Poulsen HS. EGFR induces expression of IRF-1 via STAT1 and STAT3 activation leading to growth arrest of human cancer cells. Int. J. Cancer, 122(2):342-9, 2008. (click here to open pubmed link)

2007:
Zandi R, Larsen AB, Andersen P, Stockhausen MT, Poulsen HS. Mechanisms for Oncogenic Activation of the Epidermal Growth Factor Receptor. Cellular Signalling, 19(10): 2013-2023, 2007. (click here to open pubmed link)

Grandal MV, Zandi R, Pedersen MW, Willumsen BM, Van Deurs B, Poulsen HS. EGFRvIII escapes downregulation due to impared internalization and sorting to lysosomes. Carcinogenesis, 28(7):1408-17, 2007 (click here to open pubmed link)

Larsen AB, Pedersen MW, Stockhausen M, Grandal MV, van Deurs B, Poulsen HS. Activation of the EGFR target gene EphA2 inhibits EGF-induced cancer cell motility. Mol Cancer Res, Mar;5(3):283-293, 2007. (click here to open pubmed link)

N. Pedersen, T.T. Poulsen, H. Skovgaard Poulsen. Cre/loxP recombination vectors for promoter studies. Electron J Biotechol, 10:315-321, 2007. (click here to read article)

2006:
Villingshoj M, Ross L, Thomsen BL, Johansen C. Does marital status and altered contact with the social network predict colorectal cancer survival? Eur J Cancer. Nov;42(17):3022-7, 2006. (click here to open pubmed link)

Spindler K-LG, Olsen DA. Nielsen JN, Brandslund I, Poulsen HS, Villingshøj M, Jakobsen A. Lack of the Type III Epidermal Growth Factor Receptor Mutation in Colorectal Cancer. Anticancer Res., Nov-Dec; 26(6C):4889-4893, 2006. (click here to open pubmed link)

Andersen PB, Blinkenberg M, Lassen U, Kosteljanetz M, Wagner A, Poulsen HS, Sorensen PS, Paulson OB. A prospective PET study of patients with glioblastoma multiforme. Acta Neurol Scand, 113(6):412-8, 2006. (click here to open pubmed link)

Poulsen HS. Gliomer hos voksne: Primær ikke-kirurgisk behandling. Ugeskr Læger, 168(47):4082, 2006. (click here to open pubmed link)

Pedersen M.W., Poulsen HS. Mutationer i EGF receptoren: struktur og tumorbiologisk relevans. Ugeskr Læger, 168:2354-2361, 2006. (click here to open pubmed link)

J. Vestergaard, M.W. Pedersen, N. Pedersen, C. Ensinger, Z. Tümer, N. Tommerup, H. Skovgaard Poulsen, L.A. Larsen: Hedgehog signaling in small-cell lung cancer: frequent in vivo but a rare event in vitro. Lung Cancer, 52:281-90, 2006. (click here to open pubmed link)

N. Pedersen, S.E. Hansen, A.V. Heydenreich, H.G. Kristensen, H. Skovgaard Poulsen: Solid lipid nanoparticles can effectively bind DNA, streptavidin and biotinylated ligands. Eur J Pharm Biopharm, 62:155-162, 2006. (click here to open pubmed link)

Pedersen N, Pedersen MW, Lan MS, Breslin MB, Poulsen HS. The Insulinoma-Associated 1: a Novel Promoter for Targeted Cancer Gene Therapy for Small Cell Lung Cancer. Cancer Gene Ther, 13:375-384, 2006. (click here to open pubmed link)

2005:
Pedersen MW, Pedersen N, Ottesen, LH, Poulsen HS.  Differential response to gefinitib of cells expressing normal EGFR and the mutant EGFRvIII. Br J Cancer, 93:915-23, 2005. (click here to open pubmed link)

Poulsen TT, Pedersen N, Perin MS, Hansen CK, Poulsen HS. Specific sensitivity of small cell lung cancer cell lines to the snake venom Toxin, Taipoxin. Lung Cancer, 50 (3):329-337, 2005. (click here to open pubmed link)

Pedersen MW, Pedersen N, Damstrup L, Villingshøj M, Sønder SU, Rieneck K, Bovin LF, Poulsen HS. Analysis of the epidermal growth factor receptor specific transcriptome: effect of expression level and an activating mutation. J Cell Biochem, 96(2):412-27, 2005. (click here to read supplementary data) (click here to open pubmed link)

H. Collatz Christensen, J. Schüz, M. Kosteljanetz, H. Skovgaard Poulsen, J. D. Boice, Jr., J. K. McLaughlin and C. Johansen. Cellular telephones and risk for brain tumors. Neurology, 64:1189-1195, 2005. (click here to open pubmed link)

Poulsen TT, Pedersen N, Poulsen HS. Replacement and suicide gene therapy for targeted treatment of lung cancer. Clinical Lung Cancer, 6(4): 227-236, 2005. (click here to open pubmed link)

2004:
Pedersen N, Pedersen MW, Poulsen TT, Mortensen S, Sørensen SB, Rieneck K, Bovin LF, Poulsen HS. New targets and treatment of small cell lung cancer. Chest. 125: 154S, 2004. (click here to open pubmed link)

Collatz HC, Schüz J, Kosteljanetz M, Poulsen HS, Thomsen J, Johansen C. Cellular telephone use and risk for acoustic neurinoma. Am J Epidemiol. 159(3): 277-83, 2004. (click here to open pubmed link)

Pedersen MW, Tkach V, Pedersen N, Berezin V and Poulsen HS. A naturally occuring constitutive active variant of the epidermal growth factor receptor increases cell motility. Int. J. Cancer 108:943-653, 2004. (click here to open pubmed link)

2003:
Heidenreich AV, Westmeier R, Pedersen N, Poulsen HS, Kristensen HG. Preparation and purification of cationic nanospheres - effects on particle size, physical stability and cell toxicity. Int. J. Pharm. 254:83-87, 2003. (click here to open pubmed link)

Schimiegelow M, Feldt-Rasmussen U, Rasmussen AK, Lange M, Poulsen HS, Müller J. Assessment of the Hypothalamo-Pituitary-Adrenal Axis in Patients treated with Cranial Radiotherapy for a Childhood Brain Tumor. J Clin Endocrinol Metab. Jul. 88(7):3149-54, 2003. (click here to open pubmed link)

Nielsen KL, Allen MR, Bloomfield SA, Andersen TL, Chen X, Xu T, Poulsen HS, Young MF, Heegaard M. Biglycan Deficiency interferes with overiectomy-induced bone loss. J Bone Miner Res. 18(12):2152-2158, 2003. (click here to open pubmed link)